Giant Congenital Melanocytic Nevus Treated With Trametinib
نویسندگان
چکیده
منابع مشابه
Giant congenital melanocytic nevus*
Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis), and have major ps...
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Figure 1. Two-year-old boy with a giant congenital melanocytic nevus of the left buttock. Left, Center, Preoperative views. Right, Immediate view after excision and placement of the Integra bilayer matrix dressing. Figure 2. Left, Wound after removal of the silicone layer of the Integra bilayer matrix dressing. Right, Coverage of the wound with a split skin autograft.
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Garment-like giant congenital melanocytic nevi are very rare, and those being treated are most often offered excision and split-thickness skin transplantation. Due to the risk of restricted mobility secondary to shrinkage and hypertrophic scarring of the transplant, we treated to date the largest reported giant congenital melanocytic nevus (16% total body surface area) with Integra dermal regen...
متن کاملBlaschkolinear congenital melanocytic nevus.
common acquired nevi and an otherwise normal clinical examination. Congenital melanocytic nevi are often classified according to their size [1] . Another attempt of classification in two groups has recently been proposed: type I, the most frequent, with a single lesion involving one anatomic area and type II, less common, with a larger lesion and dozens of smaller ones, with a similar pattern o...
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During the normal development of skin, pluripotential cells give rise to keratinocytes, sebaceus glands, hair follicles, apocrine glands and eccrine glands. A hamartoma, or an abnormal mixture of a tissue’s normal components, results from an error in development, among which some show malignant potential. We report two Chinese cases of giant congenital cutaneous hamartoma, a nevus sebaceus of J...
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ژورنال
عنوان ژورنال: Pediatrics
سال: 2019
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2018-2469